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Acute carbon monoxide poisoning with coexisting cerebral and myocardial infarction: The brain-heart connection and challenges of management in resource-limited settings Acta Toxicol. Argent.
Oghuvwu,Sunday Omokiniovo; Isah,Ambrose Ohumagho; Opadeyi,Abimbola; Ayinbuomwan,Stephen A.
Carbon monoxide poisoning pose significant public health consequence and management can be challenging in resource-poor countries. This is a commentary of a 40 year-old farmer with a five day history of loss of consciousness following overnight inhalation of carbon monoxide. Neuroimaging and electrophysiologic studies showed bilateral internal capsule and myocardial infarction. He had unsuccessful treatment with normobaric oxygen therapy in the absence of hyperbaric oxygen. This case depicts the brain-heart connection in carbon monoxide poisoning and highlights the challenges of management in a resource poor setting.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Carbon monoxide; Poisoning; Acute; Infarction.
Ano: 2018 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-37432018000200004
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Acute stress-induced antinociception is cGMP-dependent but heme oxygenase-independent BJMBR
Carvalho-Costa,P.G.; Branco,L.G.S.; Leite-Panissi,C.R.A..
Endogenous carbon monoxide (CO), which is produced by the enzyme heme oxygenase (HO), participates as a neuromodulator in physiological processes such as thermoregulation and nociception by stimulating the formation of 3′,5′-cyclic guanosine monophosphate (cGMP). In particular, the acute physical restraint-induced fever of rats can be blocked by inhibiting the enzyme HO. A previous study reported that the HO-CO-cGMP pathway plays a key phasic antinociceptive role in modulating noninflammatory acute pain. Thus, this study evaluated the involvement of the HO-CO-cGMP pathway in antinociception induced by acute stress in male Wistar rats (250-300 g; n=8/group) using the analgesia index (AI) in the tail flick test. The results showed that antinociception...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Heme oxygenase; Carbon monoxide; CGMP; Lateral cerebral ventricle; Acute stress; Antinociception.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001201057
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Antinociception synergy between the peripheral and spinal sites of the heme oxygenase-carbon monoxide pathway BJMBR
Nascimento,C.G.O.; Branco,L.G.S..
We have shown that the peripheral and spinal cord heme oxygenase (HO)-carbon monoxide (CO)-soluble guanylate cyclase-cGMP pathways play an important role in antinociception in the rat experimental formalin model. Our objective was to determine if there is synergism between peripheral (paw) and spinal HO-CO pathways in nociception. Rats were handled and adapted to the experimental environment for a few days before the formalin test, in which 50 µL of a 1% formalin was injected subcutaneously into the dorsal surface of the right hind paw. The animals were then observed for 1 h and the frequency of flinching behavior was taken to represent the nociceptive response. Thirty minutes before the test, rats were pretreated with intrathecal injections of the HO...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nociception; Carbon monoxide; Formalin; Hypernociception; Antinociception.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000100020
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Carbon monoxide: from toxin to endogenous modulator of cardiovascular functions BJMBR
Johnson,R.A.; Kozma,F.; Colombari,E..
Carbon monoxide (CO) is a pollutant commonly recognized for its toxicological attributes, including CNS and cardiovascular effects. But CO is also formed endogenously in mammalian tissues. Endogenously formed CO normally arises from heme degradation in a reaction catalyzed by heme oxygenase. While inhibitors of endogenous CO production can raise arterial pressure, heme loading can enhance CO production and lead to vasodepression. Both central and peripheral tissues possess heme oxygenases and generate CO from heme, but the inability of heme substrate to cross the blood brain barrier suggests the CNS heme-heme oxygenase-CO system may be independent of the periphery. In the CNS, CO apparently acts in the nucleus tractus solitarii (NTS) promoting changes in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Carbon monoxide; Heme; Heme oxygenase; Blood pressure; Central nervous system; Vascular tone.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000100001
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US and German Consumer Preferences for Ground Beef Packaged Under a Modified Atmosphere AgEcon
Grebitus, Carola; Jensen, Helen H.; Roosen, Jutta.
Consumers' preferences for meat quality attributes such as color influence their purchasing decisions. Better understanding of consumer preferences can help meat processors and others attain effective product development and marketing and inform public policy decisions on nutrition and food safety education. Modified atmosphere packaging extends the shelf-life of fresh meat and, with the inclusion of carbon monoxide, achieves dramatic color stabilization. The value that US and German consumers' place on ground beef packaging techniques was quantifies by means of non-hypothetical choice experiments. The studies' results can benefit food producers and retailers who make decisions about investing in new packaging methods by providing quantitative measures of...
Tipo: Conference Paper or Presentation Palavras-chave: Ground beef; Modified atmosphere packaging; Carbon monoxide; Consumer purchasing decisions; Preferences; Willingness to pay; Cross-country study; Agricultural and Food Policy; Consumer/Household Economics; Demand and Price Analysis; Food Consumption/Nutrition/Food Safety; Food Security and Poverty; Health Economics and Policy.
Ano: 2010 URL: http://purl.umn.edu/116412
Registros recuperados: 5
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